Quote:
Originally Posted by rocknation
Don't forget that Tico's appendix and gall bladder abruptly left the tour, too! 
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I wouldn't say there is a direct link between Ticos gall bladder and Jon's grey hair.
I'm sure the stress is from touring and managing the band overall. Being away from his family at this age as well as dealing with the business side of his band can definately age someone quickly.