I had that dream come true when I saw the Band at The O2 in 2007 and Twickenham in 2008
Was at Twickenham and didn't like Prayer as the opener. I think its the perfect main set closer. Everything builds to that song and keeps the majority of the crowd interested. I found the atmosphere tailed off pretty quick after it was played that day. Nothing for the casual fan to look forward to.
I watched the recent videos and I think you give love a bad name works really well they can do that or try I believe or prayer. But raise your hands is the best opener ever in my opinion.