I start using when I was 16, 26 now so for 10 years....
I really tried it all, even heroin once although I thought it was cocaine at that time...
Sure there were times when it was completely out of control, period 18-20. But it was always occasional, the line was crossed a few times but still.....
I never had physical problems not using it. Of course sometimes I really wanted to use something but somehow at those times I never did. I almost always needed a occasion for it...
As long as you keep it in the lines of occasional, its the best thing ever...
And as long as it's occasional, it doesn't do much more harm (if not less) then alcohol (not counting heroin, crack) and again it's much more fun
Time for new era for me now, but never regretted, had the best nights of my life with it, did the weirdest & craziest stuff on it...

It's prejudice to say it's **** you up when claiming to be drunk on same ratio (and having a hangover the next day )

And of course its works different on every person. I know someone who gets completely ****ed up after two shots of alcohol...

(oh and it never got into my social or proffesional life, hell it made my time at the uni a succes)